The Integrative Functional Regenerative Medicine Approach
A comprehensive three-tiered therapeutic strategy designed to address the multifactorial nature of combination inflammatory dermatoses through cellular, physical, and metabolic interventions.
Core Therapeutic Modalities
Our approach is built upon the principle that overlapping chronic inflammatory skin conditions require multimodal intervention. Umbilical cord mesenchymal stem cells serve as the foundational biological component, while physical therapy and nutritional medicine provide the essential supportive framework.
Cellular Immunomodulation Core
Umbilical cord-derived mesenchymal stem cells are utilized for their immunomodulatory properties. These cells, along with their derivatives (exosomes), are administered through minimally invasive techniques to engage with mixed inflammatory pathways and support skin barrier repair.
Physical Medicine Integration
Customized supportive plans focus on stress reduction, lymphatic flow, and overall physiological balance. Physical medicine techniques support the body's regenerative capacity and complement the cellular therapy.
Nutritional Support
Nutritional medicine strategies are employed to reduce systemic inflammation, support skin barrier function, and provide substrates necessary for tissue repair. IV fluid therapies with multivitamins integrate to support overall treatment response.
Clinical procedure visualization
Core Therapeutic Benefits
Umbilical cord mesenchymal stem cells and their derivatives offer multiple mechanisms of action in the adjunctive management of combination inflammatory dermatoses.
Mixed Inflammation Modulation
Reduction of pruritus, erythema, scaling, and inflammatory flares through broad immunomodulatory mechanisms targeting Th1, Th2, and Th17 cytokines.
Skin Barrier Restoration
Supports ECM remodeling, promotes filaggrin, loricrin, and ceramide synthesis, and reinforces skin barrier integrity across overlapping conditions.
Immunoprivileged & Proliferative
UC-MSCs exhibit immunoprivileged characteristics, reducing alloreactivity while supporting local immune homeostasis.
Mechanistic references: MSC paracrine signaling in inflammatory skin disorders (PubMed) | Systematic review: MSCs for inflammatory dermatoses (PMC) | Clinical insights (ClinicalTrials.gov)
Key Mechanisms of UC-MSC & Derivatives in Mixed Inflammatory Skin Conditions
Your Adjunctive Regenerative Journey: A Practical Guide
Download our comprehensive walkthrough detailing the overall experience: from local travel logistics, lodging, and transportation services to payment methods. The guide also includes technical information on umbilical stem cells and derivatives (exosomes), supportive multivitamin IV fluid therapies, and essential pre- & post-treatment recommendations.
This resource provides objective information about supportive approaches and helps you plan your visit with clarity.
Download the Guide
We respect your privacy. Your information will not be shared.
Ideal Candidate Profile
The integrative regenerative medicine approach is designed for individuals with combination inflammatory dermatoses who have not achieved satisfactory improvement through conventional therapies alone. Appropriate candidates typically present with moderate-to-severe overlapping inflammatory skin conditions where immune dysregulation and barrier dysfunction are contributing factors.
Ideal candidates are generally those with chronic inflammatory patterns who maintain realistic expectations and are committed to participating in the comprehensive supportive protocols that accompany the cellular component of treatment.
- Diagnosed combination inflammatory dermatoses (e.g., overlapping psoriasis, atopic dermatitis, seborrheic dermatitis features)
- Chronic inflammatory flares persisting despite conventional management
- Inadequate response to topical or systemic immunosuppressants
- Absence of active cutaneous infections
- Realistic expectations regarding outcomes and timeline
- Commitment to participate in supportive physical and nutritional therapies
- Absence of contraindications to regenerative procedures
Candidate Evaluation
Comprehensive medical assessment to determine appropriateness for adjunctive regenerative intervention.
Important clinical note: This adjunctive approach is not a replacement for conventional treatments for combination inflammatory dermatoses. Patients should continue those treatments under the direction of their prescribing physician.
MSC adjunctive therapy for combination inflammatory dermatoses is not approved by the U.S. FDA, Mexican COFEPRIS (for this indication), or any other regulatory agency. It is considered an adjunctive, supportive procedure. Costs are discussed only after a consultation.
Professional Clinical Perspective
As medical professionals specializing in regenerative medicine, we approach combination inflammatory dermatoses with a commitment to evidence-based practice and patient-centered care. Our integrative functional approach recognizes that successful outcomes often require addressing multiple contributing factors simultaneously.
We emphasize transparent communication regarding the current scientific understanding of regenerative techniques, the importance of supportive therapies, and the need for realistic expectations. Each treatment plan is individualized based on comprehensive evaluation, patient history, and specific clinical factors.
Our practice maintains a focus on safety, procedural precision, and thorough follow-up care to monitor progress and adjust supportive therapies as needed throughout the regenerative process.
— Nexus Regenerative Medicine Clinical Team